Overweight volunteers who took a new experimental drug lost about 6 pounds in one year.
Those who took medication, had less desire to eat sweet foods and foods containing starch.
They felt satiate and appetite decreased.
The study, published in the medical journal “Lancet” (Lancet), shows that the side effects of the drug were mild and resolved with time.
Experts cautioned, however, that additional studies are needed before it can be stated that the drug is safe.
Data from company-sponsored study already provided to management for control of foodstuffs and medicines in the U.S., where a panel of experts should consider by December whether to approve the sale of the drug.
The drug is a combination of antidepressant bupropion and naltrexone, used to treat alcoholism and other addictive.
The study covers 1700 patients with overweight or obese, some of them received a placebo and the remaining one of the two versions of the drug.
Those who used the drug lost weight 6 kg per year and placebo only 1 kilogram and 400 grams. Medicines cause a slight increase in blood pressure that normalized with time.
Not identified other possible side effects specific to one component of the drug – bupropion and anxiety, insomnia and suicidal thoughts.
Three U.S. companies are struggling to obtain licenses from management control over food and medicines for a new drug against obesity.